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Carpal Tunnel Syndrome (CTS) is most common entrapment neuropathy affecting the median nerve as it passes through the carpal tunnel at the wrist.When this structure becomes irritated and inflamed, it can cause compression and narrowing of this space and its structures that are passing . Compression within this narrow passageway can lead to symptoms including pain, numbness, tingling, and weakness in the hand, particularly affecting the thumb, index, middle, and lateral half of the ring finger. Contributing Factors: a) Repetitive wrist and hand movements: Repetitive movements of the wrist and hand when doing activities such as computer mouse use, typing, assembly line work (grasping, pinching and other hand movements), sewing/knitting can all put an individual at higher risk of developing CTS. b) Sustained Hand and wrist positions: Sustained hand and wrist positions such as wrist flexion can lead to irritation of these structures which may lead to CTS. c) Anatomical factors: People can have many anatomical variations in general, with one being a potential to have a more narrow carpal tunnel region meaning that they have a more predisposed to developing a conditioning like CTS. d) Pregnancy: When people are pregnant there are a plethora of changes to the body, some being fluid retention and hormonal fluctuations which may lead to increased pressure on the median nerve and altered hand/wrist mechanics leading to increased aggravation of structures as described above. Women also have a 3-5x increased risk of developing this condition. e) Medical: Conditions such as arthritis, diabetes, obesity and other inflammatory conditions such as rheumatoid arthritis are also highly correlated with CTS. f) Wrist injuries: Having sustained previous wrist injuries such as wrist fractures in the past can also damage the carpal tunnel and other structures associated with CTS development. Management & Treatment: 1) Activity modifications and ergonomic education: Avoiding and/or minimising repetitive and sustained wrist flexion/extension movements to reduce strain. Using a more neutral positioned wrist when completing tasks will minimise stress on the wrist. Utilising ergonomic friendly keyboard/mouse and desk set ups. Education on pacing strategies for load management purposes. 2) Splinting: Wearing a wrist splint at night (night symptoms are common due to wrist flexion in sleep) and during any tasks that may be aggravating is the first line treatment. This is helpful as it keeps the wrist in neutral and not in positions like wrist flexion which can reduce irritation and compression on the median nerve. Some splints may require input from a hand therapist but this will be discussed with your physiotherapist. 3) Exercise rehab: Exercises that lookto target to increase wrist and hand strength and mobility. Exercises that also strengthen and focus to increase flexibility in surrounding muscles are important too. Specialised exercises such as nerve glides (gentle movements of the wrist/hand) can help mobilise the median nerve to minimise compression and encourage normalised movements that do not aggravate CTS related mechanics. 4) Manual therapy: Manual therapy techniques such as soft tissue work and joint mobilisations to help with releasing forearm tension/compressing factors and improving wrist mobility to mitigate pain and improve healing. Due to the median nerve involvement, including treatment to the cervical (neck) and thoracic (mid back) can help if these areas are contributing to nerve entrapment or irritation more proximally. 5) Medical/Referral imaging: In some scenarios, referral for imaging and or specialist involvement for potential surgical options may be necessary in severe cases or failed conservative approaches.